Staff profile: Professor Andy Jewell
Position: Professor, Health Sciences
Telephone: +44 (0)20 8417 7194
Email: a.jewell@sgul.kingston.ac.uk
Biography
Andy completed a BSc in physiology at the University of London before qualifying as a biomedical scientist. After working in haematology at University College Hospital, he joined the bone marrow transplant team at the Royal Free Hospital and completed an MSc in immunology at King’s College, London. He then returned to University College London to complete a PhD on the immunology of chronic lymphocytic leukaemia.
Following the successful award of a Leukaemia Research Fund post-doctoral fellowship, Andy moved to Kingston University as course director for the BSc in Biomedical Science, and later ran the haematology strand for the MSc in Biomedical Science. He recently wrote and validated the Applied Blood and Tissues pathway for the Foundation Degree in Health and Medical Sciences.
Andy currently supervises several research students working on collaborative projects in immunology and health, such as HIV and cancer, in many parts of the world, including the USA, Kenya, Nigeria, Qatar, Ethiopia and the Gambia. He is on the editorial board for International Seminars in Surgical Oncology, and regularly reviews articles for the British Journal of Haematology, Leukaemia and Lymphoma, Molecular Medicine, Vox Sanguinis, and the British Journal of Cancer.
Interests
Cancers of the immune system; molecular and immunological characteristics; role of exercise in cancer treatment; immune responses to infection and the role of breast feeding; gene therapy for malignancy; member of the Exercise and Inflammatory Research Collaboration.
Publications
Article
Mboto, CI , Davies-Russell, A , Fielder, M and Jewell, A P (2009) CD4+ lymphocyte values and trends in individuals infected with Human Immunodeficiency Virus and/or co-infected with Hepatitis C virus in The Gambia.
Meklat, Farouk , Zhang, Yana , Shariar, Masum , Ahmed, Sharif U. , Li, Wei , Voukkalis, Nikolaos , Wang, Zhiqing , Zhang, Jian , Mastulov, Suhkrob , Jewell, Andrew , Giannakouros, Thomas and Lim, Seah H. (2009) Identification of protamine 1 as a novel cancer-testis antigen in early chronic lymphocytic leukaemia.
Baou, M , Jewell, A , Muthurania, A , Wickremasinghe, R G , Yong, K L , Carr, R , Marsh, P and Murphy, J J (2009) Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells [Letter to editor].
Mboto, C.I. , Fielder, Mark , Russell, Angela and JEWELL, ANDREW (2009) Prevalence of HIV-1, HIV-2, hepatitis C and co-infection in The Gambia.
Ahmed, Sharif Uddin , Meklat, Farouk , Zhang, Jian , Mastulov, Suhkrob , Giannakouros, Thomas , Jewell, Andrew , Zhang, Yana , Lim, Seah H and Shahriar , Masum (2009) SEMG-1 expression in early stage chronic lymphocytic leukemia.
Baou, Maria , Jewell, Andrew and Murphy, John J. (2009) TIS11 family proteins and their roles in posttranscriptional gene regulation.
Meklat, Farouk , Li, Zhanfei , Wang, Zhiqing , Zhang, Yana , Zhang, Jian , Jewell, Andrew and Lim, Seah H (2007) Cancer-testis antigens in haematological malignancies.
Garrod, Rachel , Ansley, Paula , Canavan, Jane and Jewell, Andy (2007) Exercise and the inflammatory response in chronic obstructive pulmonary disease (COPD): does training confer anti-inflammatory properties in COPD?
Coffils, M. , Jewell, A.P. , Jones, L.A. and Fielder, M.D. (2007) Induction of oxidative DNA damage by Helicobacter pylori in HT29 cells.
Canavan, Jane , Garrod, Rachel , Marshall, Johanna , Jackson, David , Ansley, Paula and Jewell, Andy (2007) Measurement of the acute inflammatory response to walking exercise in COPD: effects of pulmonary rehabilitation.
Paramasivam, K , Michie, C , Opara, E and Jewell, AP (2006) Human breast milk immunology: a review.
Sali, Paula and Jewell, Andrew Paul (2006) IL-1 does not reverse the anti-proliferative effect of aspirin in breast cancer cells.
Cananvan, Jane , Robson-Ansley, Paula , Garrod, Rachel and Jewell, Andy (2006) Inflammatory response to exercise in COPD.
Morsi, H. , Yong, K.L. and Jewell, A.P. (2006) Preferential survival of acute lymphoblastic leukemia cells at 33[sup] [degrees]C is associated with up-regulation of bcl-2.
Jewell, Andrew , Cochrane, Melanie , McIntosh, Jenny , Benjamin, Reuben and Nathwani, Amit (2005) Comparison of viral vectors for gene transfer into CLL cells: efficient transduction with adeno-associated virus-8 (AAV-8).
Porakishvili, N. , Kulikova, N. , Jewell, A.P. , Youinou, P.Y. , Yong, K. , Nathwani, A. , Heelan, B. , Duke, V. , Hamblin, T.J. , Wallace, P. , Ely, P. , Clark, E.A. and Lydyard, P.M. (2005) Differential expression of CD180 and IgM by B-cell chronic lymphocytic leukaemia cells using mutated and unmutated immunoglobulin VH genes.
Hewitt, JA , Mokbel, K , Van Someren, KA , Jewell, AP and Garrod, R (2005) Exercise for breast cancer survival: the effect on cancer risk and cancer-related fatigue (CRF).
Mboto, C.I. , Davies-Russell, A. , Fielder, M. and Jewell, A.P. (2005) Hepatitis C antibodies in asymptomatic first-time blood donors in The Gambia: prevalence and risk factors.
Davies-Russell, Angela , Fielder, Mark and Jewell, Andrew (2005) Hepatocellular Carcinoma in the Gambia and the role of Hepatitis B and Hepatitis C.
Mboto, Clement , Davies-Russell, Angela , Fielder, Mark and Jewell, Andrew (2005) Hepatocellular Carcinoma in The Gambia and the role of Hepatitis B and Hepatitis C.
Jewell, A.P. (2005) Is the liver an important site for the development of immune tolerance to tumours?
Porakishvili, N. , Kardava, L. , Jewell, A.P. , Yong, K. , Glennie, M.J. , Akbar, A. and Lydyard, P.M. (2004) Cytotoxic CD4+ T cells in patients with B cell chronic lymphocytic leukemia kill via a perforin-mediated pathway.
Ranger, Gurpreet Singh , Thomas, Valerie , Jewell, Andrew and Mokbel, Kefah (2004) Elevated cyclooxygenase-2 expression correlates with distant metastases in breast cancer.
Ranger, Gurpreet Singh , Jewell, Andrew , Thomas, Valerie and Mokbel, Kefah (2004) Elevated expression of cyclooxygenase-2 in breast cancer and ductal carcinoma in situ has no correlation with established prognostic markers.
Morsi, Hisham , Yong, Kwee L and Jewell, Andrew P (2004) Evaluation of the Taguchi methods for the simultaneous assessment of the effects of multiple variables in the tumour microenvironment.
St Romaine, C , Hazlehurst, G and Jewell, A P (2004) Leucodepletion for transmissible spongiform encephalopathies.
Borthwick, N.J. , Akbar, A.A. , Buckley, C. , Pilling, D. , Salmon, M. , Jewell, A.P. and Yong, K.L. (2003) Transendothelial migration confers a survival advantage to activated T lymphocytes: role of LFA-1/ICAM-1 interactions.
Jewell, Andrew P (2002) Role of apoptosis in the pathogenesis of B-cell chronic lymphocytic leukaemia.
Porakishvili, N. , Roschupkina, T. , Kalber, T. , Jewell, A.P. , Patterson, K. , Yong, K. and Lydyard, P.M. (2001) Expansion of CD4+ T cells with a cytotoxic phenotype in patients with B-chronic lymphocytic leukaemia (B-CLL).
Jewell, A P and Yong, K L (1997) Regulation and function of adhesion molecules in B-cell chronic lymphocytic leukaemia.
Jewell, A P , Worman, C P , Giles, F J and Goldstone, A H (1997) Serum levels of TNF, IL-6 and sCD23 correlate with changes in lymphocyte count in patients with B-cell chronic lymphocytic leukaemia receiving interferon-alpha therapy.
Jewell, A. P. and Giles, F. J. (1996) Cutaneous manifestation of leishmaniasis 40 years after exposure in a patient with chronic lymphocytic leukaemia.
Jewell, A. P. (1996) Interferon-alpha, Bcl-2 expression and apoptosis in B-cell chronic lymphocytic leukemia.
Jewell, A. P. , Lydyard, P. M. , Worman, C. P. , Giles, F. J. and Goldstone, A. H. (1995) Growth factors can protect B-chronic lymphocytic leukaemia cells against programmed cell death without stimulating proliferation.
Jewell, A. P. , Worman, C. P. , Lydyard, P. M. , Yong, K. L. , Giles, F. J. and Goldstone, A. H. (1994) Interferon-alpha up-regulates bcl-2 expression and protects B-CLL cells from apoptosis in-vitro and in-vivo.
Conference or Workshop Item
Baou, Maria , Murphy, John and Jewell, Andrew P. (2005) Mode of action of Rituximab in chronic lymphocytic leukaemia: activation of Tis11b, an inducer of mRNA instability, and induction of apoptosis.
Grants
- D’Sa S (Principal Applicant); Yong K; Jewell AP; van Someren K (2005). Exercise intervention study in Multiple Myeloma. Cancer Research UK, 2006-2007
- Jewell A; Cochrane M; McIntosh J; Benjamin R; Nathwani A (2005). Comparison of viral vectors for gene transfer into CLL cells: efficient transduction with adeno-associated virus-8. Blood 106 (S1)
Students supervised
- Babatunde Adeoye
- Nader Al-Dewik
- Gill Arbane
- Jane Canavan
- Alessandro Corezzola
- James Hull
- Agnieszka Lewko
- Farouk Meklat
- Abdulfatah Onifade
- Apostolos Papachristos
